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The concept of "immunologically privileged" explains why the CNS ________.


A) has a greater immune response than the rest of the body
B) has a reduced immune response compared to the rest of the body
C) has a completely different set of immune responses
D) has more MHC markers than other tissues
E) All of the choices are correct.

F) A) and B)
G) All of the above

Correct Answer

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Which of the following is not a prion disease?


A) Scrapie
B) Creutzfeldt-Jakob disease
C) Bovine spongiform encephalopathy
D) Subacute sclerosing panencephalitis
E) All of the choices are prion diseases.

F) A) and E)
G) A) and D)

Correct Answer

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The foodborne disease that involves neurotoxin is ________.


A) gastrointestinal anthrax
B) bacillus cereus intoxication
C) botulism
D) clostridium perfringens gastroenteritis
E) All of the choices are correct.

F) A) and C)
G) A) and B)

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Tetanus differs from botulism in that ________.


A) tetanus results in flaccid paralysis while botulism paralysis is rigid
B) tetanus results from an exotoxin; botulism results from an endotoxin
C) there is a vaccine for botulism,but not for tetanus
D) muscles cannot relax in tetanus; muscles cannot contract in botulism
E) All of the choices are correct.

F) A) and B)
G) A) and C)

Correct Answer

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Treatment for Neisseria meningitidis consists of ________.


A) vancomycin
B) penicillin G orally
C) penicillin G intravenously
D) rifampin
E) tetracycline

F) B) and C)
G) All of the above

Correct Answer

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Toxoplasmosis prevention includes ________.


A) vaccination of humans
B) vaccination of cats
C) hygienic precautions
D) vector control
E) All of the choices are correct.

F) C) and E)
G) A) and D)

Correct Answer

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C

An RN is part of a team that has traveled to sub-Saharan Africa to volunteer in a medical clinic. The clinic is in an underdeveloped rural area. A 5-year-old boy is brought into the clinic with a high fever, sore throat, body aches, and weakness. Through the translator, the nurse finds out that the boy has been sick for about a week. He is noted to be barefoot and his mother reports he plays in area ponds to stay cool. -Which of the following diseases should the nurse be most concerned about,considering the patient's presentation?  


A) Meningitis
B) Tetanus
C) Polio
D) Typhoid

E) B) and D)
F) None of the above

Correct Answer

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A 20-year-old female college student is admitted to the intensive care unit from the emergency department. The patient lives in a dormitory at her university and her roommate brought her to the hospital because "she is not acting like herself." The patient was previously healthy to the roommate's knowledge, involved in campus activities, and an excellent student. The RN collects the patient's history of present illness from her roommate. About two weeks prior, the patient began feeling ill. She had nasal congestion and was diagnosed with a sinus infection at the student health clinic. However, the patient reportedly decided against taking the prescribed antibiotics because she did not believe they were necessary. She developed high fevers and one day ago began complaining of a stiff neck. That morning, she was more lethargic, making nonsensical statements, and had a fever of 105°F. Her roommate was frightened by her change in behavior and drove her to the hospital. -A lumbar puncture is performed,which confirms a diagnosis of meningitis.The pathology report indicates that the cerebral spinal fluid sample was found to have gram-positive cocci in pairs and the patient is diagnosed with pneumococcus.What is the causative organism?


A) Streptococcus pneumoniae
B) Neisseria meningitides
C) Haemophilus influenzae
D) Listeria monocytogenes

E) B) and D)
F) A) and D)

Correct Answer

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Which type of neuroglia has phagocytic capabilities in the CNS?


A) Astrocytes
B) Schwann cells
C) Macrophages
D) Microglial cells
E) Neurons

F) A) and B)
G) A) and C)

Correct Answer

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Arthrospores of Coccidioides immitis develop into ________ that will release endospores into the lungs.


A) hyphae
B) capsules
C) spherules
D) capsids
E) buds

F) C) and D)
G) A) and E)

Correct Answer

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All of the following pertain to poliomyelitis except ________.


A) summer outbreaks in the United States have been increasing recently
B) transmitted primarily by fecal-contaminated water
C) can be asymptomatic or mild with headache,sore throat,fever,and nausea
D) if virus enters the central nervous system motor,neurons can be infected and destroyed
E) caused by enterovirus

F) A) and E)
G) C) and D)

Correct Answer

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While the nervous system is believed to be free from microbiota in the healthy state,research has shown that the gut microbiome plays an important role in the development of the nervous system.

A) True
B) False

Correct Answer

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Botulism is often referred to as lockjaw.

A) True
B) False

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Prions can be destroyed by autoclaving.

A) True
B) False

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An RN is part of a team that has traveled to sub-Saharan Africa to volunteer in a medical clinic. The clinic is in an underdeveloped rural area. A 5-year-old boy is brought into the clinic with a high fever, sore throat, body aches, and weakness. Through the translator, the nurse finds out that the boy has been sick for about a week. He is noted to be barefoot and his mother reports he plays in area ponds to stay cool. -Serological testing on the patient's cerebral spinal fluid confirms a diagnosis of polio.What is the best treatment modality?  


A) Antibiotics and fever control
B) Acyclovir and pain control
C) Immunization and respiratory support
D) Pain control and respiratory support

E) B) and C)
F) A) and B)

Correct Answer

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Polio virus initially multiplies in the ________.


A) liver
B) CNS
C) oropharynx and intestine
D) nasal mucosa
E) None of the choices are correct.

F) B) and E)
G) D) and E)

Correct Answer

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C

Prophylactic rifampin is indicated for individuals in close contact with patients infected by ________.


A) Neisseria menigitidis
B) Listeria monocytogenes
C) Cryptococcus neoformans
D) Coccidiodes immitis
E) Streptococcus agalactiae

F) All of the above
G) None of the above

Correct Answer

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Tetanus can be prevented with the DTaP childhood immunization and boosters of the tetanus toxoid.

A) True
B) False

Correct Answer

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Spongiform encephalopathies are ________.


A) associated with abnormal,transmissible protein in the brain
B) chronic,fatal infections of the nervous system
C) caused by prions
D) Creutzfeldt-Jakob disease,kuru,and Gerstmann-Straussler-Scheinker syndrome
E) All of the choices are correct.

F) C) and D)
G) A) and E)

Correct Answer

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Which of the following pertains to both tetanus and foodborne botulism?


A) Occurs when spore-contaminated soil enters deep wounds
B) Caused by enterotoxins of the pathogen
C) Exotoxin blocks acetylcholine release
D) Nausea and diarrhea are symptoms
E) Treatment involves antitoxin therapy

F) All of the above
G) A) and E)

Correct Answer

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E

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