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A primer of ____ is needed at the origin of nucleotide addition.


A) polymerase III
B) polymerase I
C) helicase
D) RNA
E) DNA

F) D) and E)
G) B) and E)

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Which of the following is not true of transposons?


A) can change pigmentation
B) can replace damaged DNA
C) can transfer drug resistance
D) can change the genome
E) are always part of plids

F) C) and D)
G) B) and E)

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The antiparallel arrangement within DNA molecules refers to


A) each base bonding at the 1'position of the sugar.
B) a purine always bonding to a pyrimidine.
C) one helix strand that runs from the 5'to 3'direction and the other strand runs from the 3'to 5'direction.
D) an original parent DNA strand and one newly synthesized DNA strand comprising a new DNA molecule.

E) A) and D)
F) A) and C)

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Which is incorrect about inducible operons?


A) have genes turned off by a buildup of end product
B) often encode enzymes for catabolic pathways
C) are normally turned off
D) are turned on by the substrate of the enzyme
E) include the lac operon

F) A) and D)
G) B) and D)

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The three-base sequence on DNA that codes for an amino acid is called an)


A) codon.
B) exon.
C) anticodon.
D) intron.
E) triplet.

F) A) and D)
G) B) and C)

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The RNA molecules that carry amino acids to the ribosomes during protein synthesis are called


A) ribosomal RNA.
B) messenger RNA.
C) transfer RNA.
D) primer RNA.
E) ribozymes.

F) A) and C)
G) A) and B)

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Split genes


A) are common in prokaryotes and eukaryotes.
B) only have exons initially transcribed to mRNA.
C) have introns located only at the beginning and end of a coding region.
D) require spliceosomes to excise introns and then join exons.
E) All of these choices are correct.

F) A) and B)
G) A) and C)

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DNA photolyase, in the presence of visible light, can repair DNA damage due to ultraviolet radiation.

A) True
B) False

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DNA polymerase I


A) removes primers.
B) adds bases to new DNA chain.
C) seals DNA gaps.
D) proofreads DNA chain.
E) All of these choices are correct,

F) C) and E)
G) A) and B)

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RNA molecules differ from DNA molecules because only RNA


A) has ribose.
B) has uracil.
C) is typically one strand of nucleotides.
D) does not have thymine.
E) All of these choices are correct.

F) A) and E)
G) A) and D)

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What type of mutation alters the base, but not the amino acid being coded for?


A) silent
B) back
C) point
D) nonsense
E) missense

F) B) and C)
G) All of the above

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Folding of the 5'end of a mRNA, such that binding to the ribosome is altered, is most likely to affect


A) replication.
B) transcription.
C) translation.
D) transformation.

E) None of the above
F) All of the above

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The most damaging type of mutation is a


A) point mutation.
B) silent mutation.
C) frameshift mutation.
D) back mutation.
E) All the choices are equally damaging.

F) All of the above
G) A) and D)

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Lactose is a corepressor in the lac operon.

A) True
B) False

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If the wild type DNA sequence reads THE CAT ATE THE BIG RAT, what type of mutation would change the sequence to THE CAT ATE THE BAG RAT?


A) missense
B) nonsense
C) insertion
D) deletion
E) silent

F) A) and C)
G) B) and C)

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The smallest unit of heredity is a chromosome.

A) True
B) False

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The site where the old DNA strands separate and new DNA strands will be synthesized is called the


A) primer.
B) Okazaki fragment.
C) template.
D) rolling circle.
E) replication fork.

F) C) and D)
G) A) and E)

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The lactose repressor


A) is transcribed with the structural lac genes.
B) is activated by binding lactose.
C) is inactivated by binding lactose.
D) requires lactose for its transcription.

E) All of the above
F) C) and D)

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DNA polymerase can only add new nucleotides to the old 3'DNA end.

A) True
B) False

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If a codon for alanine is GCA. What is the anticodon?


A) GCA
B) CGT
C) ACG
D) CGU
E) UGC

F) A) and D)
G) A) and E)

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